Panamanian baseball players have left a significant mark on Major League Baseball (MLB). Mariano Rivera, considered the greatest closer of all time, tops this list. He is the Panamanian with the most hits (2,705) and the only player to be inducted into the Hall of Fame in 2019 with 100% of the vote. In the offensive department, Carlos Lee stands out as the Panamanian leader in home runs (358) and second in hits (2,273), establishing himself as one of the most productive hitters from the country in MLB. Speed and impact on championship teams have one of their greatest exponents in Omar Moreno. The fourth no-hitter in the team's history with a Panamanian player occurred in the 2015 season with Cole Hamels.
